Genetically-encoded fluorescent biosensors
- Direct expression in cells
- No exogenous chemical compounds or cofactors required
- High selectivity and sensitivity
Evrogen genetically-encoded fluorescent biosensors are complex chimeric proteins combining a fluorescent protein (FP) and a sensor protein (SP) fused in a specific way. They demonstrate clearly detectable changes in fluorescence in response to a cell event of interest, which causes conformational changes of SP due to binding or reaction with a target molecule.
Evrogen biosensors allow real in vivo measuring signals in natural intracellular surround as well as precise targeting into various subcellular compartments or animal tissues.
Evrogen offers genetically-encoded fluorescent indicators for monitoring changes in intracellular concentration of important molecules, including calcium ions (Ca2+) and hydrogen peroxide (H2O2).
Available indicators
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HyPer
The first genetically-encoded fluorescent sensor capable for high-specific detection of intracellular hydrogen peroxide, one of the main ROS generated by cells
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Case12
High dynamic range genetically-encoded fluorescent sensor for detection of intracellular Ca2+ changes
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Related products
| PRODUCT | CAT.# | DESCRIPTION | SIZE | PRICE |
The prices do not include delivery. The prices vary in different countries. Please contact your local distributor for exact prices and delivery information.
The products are not available in certain countries. Please contact Evrogen or your local distributor before ordering. |
 | | Expression/source vectors | | |
|---|
| pHyPer-Cyto | FP941 | Mammalian expression vector allowing HyPer expression in cytosol under the control of CMV promoter | 20 μg | € 600.00 |
| pHyPer-dMito | FP942 | Mammalian expression vector encoding mitochondria-targeted HyPer | 20 μg | € 600.00 |
| pCase12-Cyto | FP991 | Mammalian expression vector allowing Case12 expression in cytosol under the control of CMV promoter | 20 μg | € 600.00 |
| | Vector sets | | |
|---|
| HyPer vector set | FPS01 | pHyPer-Cyto and pHyPer-dMito vectors encoding cytosolic and mitochondria-targeted forms of HyPer (a fluorescent indicator of hydrogen peroxide) | 20 μg each | € 800.00 |
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