RESEARCH PRODUCTS/Genetically-encoded fluorescent biosensors:


    HyPer

Hydrogen peroxide sensor HyPer

- Ratiometric measurement of intracellular hydrogen peroxide - Direct expression in cells
- No exogenous chemical compounds or cofactors required
- High selectivity and sensitivity
- No artifactual ROS generation
- Recommended for monitoring hydrogen peroxide production inside living cells under various physiological and pathological conditions

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HyPer expression/source vectors

pHyPer-Cyto FP941 Mammalian expression vector allowing HyPer expression in cytosol under the control of CMV promoter 20 μg € 600.00
pHyPer-dMito FP942 Mammalian expression vector encoding mitochondria-targeted HyPer 20 μg € 600.00
Gateway® HyPer-AS entry clone FP943 Gateway® entry clone for transfer of HyPer into a Gateway® destination vector; HyPer codon usage is optimized for expression in Arabidopsis and Saccharomyces 20 μg € 600.00


Vector set

HyPer FPS01 pHyPer-Cyto and pHyPer-dMito vectors encoding cytosolic and mitochondria-targeted forms of HyPer (a fluorescent indicator of hydrogen peroxide) 20 μg each € 800.00

Notice to Purchaser:

The HyPer-related materials (also referred to as "Products") are intended for research use only. These products are covered by Evrogen Patents and/or Patent applications pending.

Some elements of these materials may be also covered by third party patents issued and applicable in certain countries. No license under these patents is conveyed expressly or by implication to the recipient of the materials. Users of these materials may be required to obtain a patent license depending upon the particular application and country in which the materials are received or used.

The CMV promoter is covered under U.S. Patents 5,168,062 and 5,385,839, and its use is permitted for research purposes only. Any other use of the CMV promoter requires a license from the University of Iowa Research Foundation, 214 Technology Innovation Center, Iowa City, IA 52242.

Invitrogen Gateway® Technology: please see Limited Use Label License No. 19: Gateway® Cloning Products.

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